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Brian R Murphy Selected Research

Paramyxoviridae Infections (Parainfluenza)

12/2015Evaluation of a Live-Attenuated Human Parainfluenza Type 1 Vaccine in Adults and Children.
4/2010Mucosal parainfluenza virus-vectored vaccine against Ebola virus replicates in the respiratory tract of vector-immune monkeys and is immunogenic.
1/2009Chimeric human parainfluenza virus bearing the Ebola virus glycoprotein as the sole surface protein is immunogenic and highly protective against Ebola virus challenge.
4/2007An improved method for the recovery of recombinant paramyxovirus vaccine candidates suitable for use in human clinical trials.
10/2006Live vaccines for human metapneumovirus designed by reverse genetics.
3/2006Transmissibility, infectivity and immunogenicity of a live human parainfluenza type 3 virus vaccine (HPIV3cp45) among susceptible infants and toddlers.
11/2005Recombinant newcastle disease virus expressing a foreign viral antigen is attenuated and highly immunogenic in primates.
9/2005Human parainfluenza virus type I (HPIV1) vaccine candidates designed by reverse genetics are attenuated and efficacious in African green monkeys.
1/2005New generation live vaccines against human respiratory syncytial virus designed by reverse genetics.
12/2004Recombinant human Metapneumovirus lacking the small hydrophobic SH and/or attachment G glycoprotein: deletion of G yields a promising vaccine candidate.
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Brian R Murphy Research Topics

Disease

26Infections
05/2014 - 02/2002
15Paramyxoviridae Infections (Parainfluenza)
12/2015 - 07/2002
14Dengue (Dengue Fever)
03/2013 - 12/2002
11Viremia
03/2013 - 09/2003
5Respiratory Tract Diseases (Respiratory Tract Disease)
12/2004 - 02/2002
3Influenza in Birds (Avian Flu)
02/2010 - 11/2007
3Virus Diseases (Viral Diseases)
03/2006 - 05/2002
3Human Influenza (Influenza)
01/2006 - 01/2002
2Yellow Fever
05/2014 - 06/2008
2Tick-Borne Encephalitis (Encephalitis, Tick Borne)
09/2010 - 02/2008
2Hepatocellular Carcinoma (Hepatoma)
01/2010 - 12/2004
2Exanthema (Rash)
11/2009 - 09/2004
2Severe Acute Respiratory Syndrome
06/2007 - 06/2004
2Intussusception
09/2005 - 04/2003
1Breast Neoplasms (Breast Cancer)
12/2021
1Heart Failure
10/2015
1Hemorrhage
10/2015
1Acute Coronary Syndrome
10/2015
1Dyspnea (Shortness of Breath)
10/2015
1Venous Thrombosis (Deep-Vein Thrombosis)
03/2015
1Pulmonary Embolism
03/2015
1Venous Thromboembolism
03/2015
1Severe Dengue
02/2011
1Stomach Neoplasms (Stomach Cancer)
03/2010
1Encephalitis (Encephalitis, Rasmussen)
10/2009
1Flavivirus Infections
10/2009
1St. Louis Encephalitis
08/2008
1Respiratory Syncytial Virus Infections
10/2007
1Fever (Fevers)
03/2006
1Neuroblastoma
01/2006
1Diarrhea
09/2005
1Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome)
12/2004
1Neutropenia
09/2004
1Measles
12/2002

Drug/Important Bio-Agent (IBA)

44VaccinesIBA
12/2015 - 01/2002
16Proteins (Proteins, Gene)FDA Link
09/2010 - 09/2003
15Neutralizing AntibodiesIBA
08/2011 - 02/2002
7AntigensIBA
09/2008 - 02/2002
5AntibodiesIBA
03/2011 - 06/2004
4Attenuated VaccinesIBA
02/2011 - 12/2002
4NucleotidesIBA
08/2008 - 09/2003
2EnzymesIBA
01/2010 - 09/2004
2Glycoproteins (Glycoprotein)IBA
01/2009 - 08/2008
23' Untranslated Regions (3' UTR)IBA
08/2008 - 01/2005
2Interferon Type IIBA
08/2008 - 03/2006
2Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
06/2007 - 12/2002
2Rotavirus VaccinesIBA
09/2005 - 04/2003
2Combined VaccinesIBA
05/2005 - 01/2005
1Hormones (Hormone)IBA
12/2021
1Cyclin-Dependent Kinases (cdk Proteins)IBA
12/2021
1ErbB Receptors (EGF Receptor)IBA
12/2021
1TicagrelorIBA
10/2015
1Prasugrel HydrochlorideFDA Link
10/2015
1Warfarin (Coumadin)FDA LinkGeneric
03/2015
1A-factor (Streptomyces)IBA
03/2013
1Neuraminidase (Sialidase)IBA
02/2010
1Hemagglutinins (Hemagglutinin)IBA
02/2010
1Dihydrotachysterol (AT 10)IBA
01/2010
1Alanine Transaminase (SGPT)IBA
11/2009
1Influenza Vaccines (Influenza Vaccine)FDA Link
06/2009
1Interferon-betaIBA
02/2009
1Membrane Proteins (Integral Membrane Proteins)IBA
01/2009
1Viral AntigensIBA
09/2008
1Caspase 3 (Caspase-3)IBA
09/2008
1Respiratory Syncytial Virus VaccinesIBA
10/2007
1Membrane Glycoproteins (Membrane Glycoprotein)IBA
06/2007
1CytokinesIBA
06/2007
1Nucleocapsid ProteinsIBA
06/2007
1HN ProteinIBA
11/2005
1Viral ProteinsIBA
08/2004
1Monoclonal AntibodiesIBA
08/2004
1SARS-CoV spike glycoproteinIBA
06/2004
1Complementary DNA (cDNA)IBA
12/2002
1Synthetic Vaccines (Recombinant Vaccines)IBA
05/2002

Therapy/Procedure

1Therapeutics
12/2021
1Patient Readmission
10/2015
1Percutaneous Coronary Intervention
10/2015
1Drug Therapy (Chemotherapy)
03/2010
1Intraperitoneal Injections
03/2006
1Intranasal Administration
06/2004